Prognostic value of apoptosis inducing factor in uveal melanoma
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چکیده
منابع مشابه
Prognostic value of legumain in uveal melanoma
The present study aimed to assess the expression of legumain in uveal melanoma (UM) cell lines and primary UM specimens, and to determine the possible association between legumain expression and clinical as well as pathological characteristics to reveal its impact on the prognosis of patients with UM. Records of primary UM cases treated at Beijing Tongren Hospital and Tianjin Eye Hospital betwe...
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Purpose: To investigate the effects of split dose irradiation on primary and metastatic uveal melanoma cell lines using a clonogenic survival assay. Methods: Appropriate cell concentrations of four primary and four metastatic human uveal melanoma cell lines were cultured for irradiation with single doses and with two equal fractions separated by 5 h. After irradiation colony formation was allow...
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OBJECTIVE To evaluate whether nuclear activity as measured by the disodium phosphate 32P (32P) uptake test for uveal melanoma is of prognostic value and corresponds to known prognostic factors. METHODS A retrospective analysis of 121 patients with choroidal and/or ciliary body melanoma, tested with the 32P uptake test before enucleation between January 1, 1973, and December 31, 1976, at the L...
متن کاملGenomic, prognostic, and cell-signaling advances in uveal melanoma.
Uveal melanoma (UM) is the second-most common form of melanoma and the most common primary intraocular malignancy. Up to one-half of patients are at risk for fatal metastatic disease. The metastatic potential of an individual tumor can be accurately determined by analysis of a fine-needle aspirate with gene expression profiling assay that is available for routine clinical use through a commerci...
متن کاملNBS1 expression as a prognostic marker in uveal melanoma.
PURPOSE Up to half of uveal melanoma patients die of metastatic disease. Treatment of the primary eye tumor does not improve survival in high-risk patients due to occult micrometastatic disease, which is present at the time of eye tumor diagnosis but is not detected and treated until months to years later. Here, we use microarray gene expression data to identify a new prognostic marker. EXPER...
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ژورنال
عنوان ژورنال: Neoplasma
سال: 2017
ISSN: 1338-4317
DOI: 10.4149/neo_2017_213